According to the Department of Transportation's Air Travel Consumer Report the top 6 most complained about travel agents for 2007 are:5. (tie) Priceline.com & Cheapoair.com
4. CheapTickets.com
3. Expedia.com
2. Travelocity.com
1. Orbitz.com
Most of Orbitz's complaints dealt with problems ticketing and boarding... and of course, refunds.
The complaints listed here represent only those formally lodged with the Dept. of Transportation.
For more fun information:
http://airconsumer.ost.dot.gov/reports/index.htm